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The concomitant use of DEMEROL Tablets or Oral Remedy and CYP3A4 or CYP2B6 inducers can lower the plasma focus of meperidine [see Medical Pharmacology (twelve.3)], leading to lowered efficacy or onset of the withdrawal syndrome in clients who definitely have formulated Bodily dependence to meperidine [see Warnings and Precautions (five.To cut

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